Promega products for Genetic identity testing include forensic DNA analysis, paternity and genetic testing. Kits are available for probabilistic genotyping, DNA sequencing for forensic labs, Y-screening and direct amplification of samples from crime victims.
Genetic Identity
Forensic DNA Analysis
Promega offers comprehensive solutions for analyzing forensic DNA samples using capillary electrophoresis (CE). This includes a range of reagents and kits covering all stages of the CE analysis workflow.
The product line features pre-processing reagents suitable for swabs and card punches, for the direct amplification of database samples, as well as DNA isolation systems tailored for casework samples. Additionally, Promega provides the PowerQuant® System for precise, human-specific DNA quantification, and the PowerPlex® Systems for STR amplification of either Y-specific or autosomal DNA, conforming to global standards. For the actual sample analysis, the Spectrum family of CE instruments caters to various needs, offering both low- and high-throughput sample processing capabilities.
Micro Satellite Instability
Known for its precision and expert support, the Promega MSI Analysis System is recognized as the premier MSI assay in clinical research.
MSI testing on tumor tissue is traditionally conducted using Polymerase Chain Reaction (PCR) and Capillary Electrophoresis (CE). This long-standing practice aims to detect functional signs of genomic instability (such as the loss of the DNA mismatch repair system), a key aspect in the study of hereditary cancers and more recently a critical, tissue-agnostic biomarker for identifying suitable candidates for cancer immunotherapies, specifically immune checkpoint inhibitors.
Genetic Analysis Software
SoftGenetics provides an extensive array of genetic analysis software tailored for both clinical and forensic uses, using a range of unique technologies to offer high sensitivity, precision, and notably low rates of false positives.
Our products include:
- Mutation Surveyor® DNA Variant and Sequence Analysis software
- NextGENe®Sequence Analysis software for “Next Generation” Sequencers
- GeneMarker® Fragment Analysis Software
- ChimeRMarker® Automated Chimerism, STR & monitoring software
- GeneMarker®HID Human Identity/STR Analysis Software
- GeneMarker®HTS Forensic NGS Software
- MaSTR™ Probablistic Software for probabilistic mixture analysis
